公开(公告)号：US07141693B2

公开(公告)日：2006-11-28

申请号：US10485495

申请日：2002-08-02

申请人： Akio Matsushita ,  Kiyotaka Yoshii ,  Masayoshi Oue ,  Taku Nakamura ,  Shuji Yamada

发明人： Akio Matsushita ,  Kiyotaka Yoshii ,  Masayoshi Oue ,  Taku Nakamura ,  Shuji Yamada

IPC分类号： C07C255/03

CPC分类号： C07C253/30 ,  C07C255/17

摘要： The present invention relates to a process for preparing a β-oxonitrile compound or an alkali metal salt thereof which comprises reacting a carboxylic ester represented by the formula (1): R1CO2R2  (1) wherein R1 and R2 each represent a group which does not participate in a reaction, provided that R2 excludes a hydrogen atom, with a nitrile compound represented by the formula (2): R3CH2CN  (2) wherein R3 represents an alkyl group, and a base at 145 to 300° C. in a sealed vessel to obtain an alkali metal salt of a β-oxonitrile compound represented by the formula (3): wherein R1 and R3 have the same meanings as defined above, and neutralizing the same with an acid, if necessary.

摘要翻译： 本发明涉及一种制备β-氧腈化合物或其碱金属盐的方法，包括使由式（1）表示的羧酸酯：<？in-line-formula description =“In-line Formula”end =“lead”？> R <1> 2 2（1）<？in-line-formula description =“在线公式 “末端”“尾”→其中R 1和R 2各自表示不参与反应的基团，条件是R 2 O >不包括氢原子与式（2）表示的腈化合物：<？in-line-formula description =“In-line formula”end =“lead”？> R 3 CN（2）<βin-line-formula description =“In-line Formulas”end =“tail”？>其中R 3表示烷基，和 在密封容器中在145-300℃的碱，得到由式（3）表示的β-氧腈化合物的碱金属盐：其中R 1和R 3， / SUP>与定义的含义相同 如果需要，用酸中和酸。

公开(公告)号：US06570015B2

公开(公告)日：2003-05-27

申请号：US10245571

申请日：2002-09-17

申请人： Akio Matsushita ,  Kiyotaka Yoshii ,  Masayoshi Oue ,  Taku Nakamura ,  Shuji Yamada

发明人： Akio Matsushita ,  Kiyotaka Yoshii ,  Masayoshi Oue ,  Taku Nakamura ,  Shuji Yamada

IPC分类号： C07D23938

CPC分类号： C07D239/38

摘要： There is disclosed a process for producing a 2-substituted thiopyrimidine-4-carboxylate represented by the formula (3): wherein R2 represents a substituted or unsubstituted hydrocarbon group and R3 represents a hydrocarbon group, which comprises reacting-an &agr;-keto ester compound represented by the formula (1): R1OCH═CHCOCO2R2  (1) wherein R1 represents a substituted or unsubstituted hydrocarbon group, and R has the same meaning as defined above, with an isothiourea compound represented by the formula (2): wherein R3 has the same meaning as defined above.

摘要翻译： 公开了由式（3）表示的2-取代硫代嘧啶-4-羧酸盐的制备方法：其中R2表示取代或未取代的烃基，R3表示烃基，其包括使α-酮酯化合物 由式（1）表示：其中R 1表示取代或未取代的烃基，R具有与上述相同的含义，与式（2）表示的异硫脲化合物：其中R3具有与上述相同的含义。

公开(公告)号：US20090137822A1

公开(公告)日：2009-05-28

申请号：US11920568

申请日：2006-05-16

申请人： Akio Matsushita ,  Kiyotaka Yoshii ,  Mizuho Oda ,  Masayoshi Oue ,  Shuji Yamada

发明人： Akio Matsushita ,  Kiyotaka Yoshii ,  Mizuho Oda ,  Masayoshi Oue ,  Shuji Yamada

IPC分类号： C07D333/38 ,  C07D333/22 ,  C07D333/16

CPC分类号： C07D333/38 ,  C07D333/22

摘要： The present invention relates to a process for preparing a 3-substituted thiophene represented by the formula (2): wherein R represents a cyano group, a formyl group, a carboxyl group, a hydrocarbyloxycarbonyl group which may have a substituent(s) or an acyl group which may have a substituent(s), which comprises reacting a vinyl compound represented by the formula (1): RCH═CHY  (1) wherein R has the same meaning as defined above, and Y represents a leaving group, and an α-mercaptoacetaldehyde or a multimer thereof.

摘要翻译： 本发明涉及一种由式（2）表示的3-取代噻吩的制备方法：其中R表示氰基，甲酰基，羧基，可具有取代基的烃氧基羰基或 可以具有取代基的酰基，其包括使由式（1）表示的乙烯基化合物：<？in-line-formula description =“In-line formula”end =“lead”→RCH-CHY （1）<？in-line-formula description =“In-line Formulas”end =“tail”？>其中R具有与上述相同的含义，Y表示离去基团，而α-巯基乙醛或多聚体 其中。

公开(公告)号：US06337416B2

公开(公告)日：2002-01-08

申请号：US09879280

申请日：2001-06-12

申请人： Hiroyuki Ikeuchi ,  Yasuhisa Sakakibara ,  Masayoshi Oue

发明人： Hiroyuki Ikeuchi ,  Yasuhisa Sakakibara ,  Masayoshi Oue

IPC分类号： C07F708

CPC分类号： C07F7/126 ,  C07F7/025 ,  C07F7/188

摘要： A (polycyclic secondary-amino)dialkoxysilane favorably employable as a catalyst for polymerization of &agr;-olefin can be prepared by reacting tetrachlorosilane, or a mono(C1-C8)alkyltrichlorosilane with a polycyclic secondary-amine in a non-hydrous, non-alcoholic organic solvent in the presence of a hydrogen chloride-trapping reagent, to produce a (polycyclic secondary-amino)chlorosilane and reacting the (polycyclic secondary-amino)chlorosilane with an alkali metal alkoxide or an alkaline earth metal alkoxide in the presence of a lower alcohol.

摘要翻译： 优选可用作α-烯烃聚合催化剂的（多环仲氨基）二烷氧基硅烷可以通过使四氯硅烷或单（C 1 -C 8）烷基三氯硅烷与非水合非醇的多环仲胺反应来制备 有机溶剂在氯化氢捕获试剂的存在下反应，生成（多环仲氨基）氯代硅烷，并使（多环仲氨基）氯硅烷与碱金属醇盐或碱土金属醇盐在较低的存在下反应 醇。