- 专利标题: Pyrazole compositions useful as inhibitors of ERK
-
申请号: US10225719申请日: 2002-08-22
-
公开(公告)号: US06593357B1公开(公告)日: 2003-07-15
- 发明人: Jeremy Green , Jingrong Cao , Michael Hale , Christopher Baker , Francois Maltais , James Janetka , Michael Mullican , Guy Bemis , Xiaoling Xie , Judith Straub , Qing Tang
- 申请人: Jeremy Green , Jingrong Cao , Michael Hale , Christopher Baker , Francois Maltais , James Janetka , Michael Mullican , Guy Bemis , Xiaoling Xie , Judith Straub , Qing Tang
- 主分类号: A61K314155
- IPC分类号: A61K314155
摘要:
Described herein are compounds that are useful as protein kinase inhibitors having the formula: where R1-4, Q, and T are described in the specification. The compounds are useful for treating disease states in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.