发明授权
US06635640B2 4-heteroaryl-3-heteroarylidenyl-2-indolinones and their use as protein kinase inhibitors
失效
4-杂芳基-3-杂芳基-2-二氢吲哚酮及其作为蛋白激酶抑制剂的用途
- 专利标题: 4-heteroaryl-3-heteroarylidenyl-2-indolinones and their use as protein kinase inhibitors
- 专利标题(中): 4-杂芳基-3-杂芳基-2-二氢吲哚酮及其作为蛋白激酶抑制剂的用途
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申请号: US09894902申请日: 2001-06-29
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公开(公告)号: US06635640B2公开(公告)日: 2003-10-21
- 发明人: Peng Cho Tang , Chung Chen Wei , Ping Huang , Jingrong Cui
- 申请人: Peng Cho Tang , Chung Chen Wei , Ping Huang , Jingrong Cui
- 主分类号: C07D40314
- IPC分类号: C07D40314
摘要:
The present invention relates to certain 4-heteroaryl-3-heteroarylidenyl-2-indolinones compounds and their physiologically acceptable salts which modulate the activity of protein kinases (“PKs”), in particular CDK2. The compounds of the present invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical composition containing these compounds and methods of preparing these compounds are also described.
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