Invention Grant
- Patent Title: Acid derivatives useful as serine protease inhibitors
- Patent Title (中): 用作丝氨酸蛋白酶抑制剂的酸衍生物
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Application No.: US10052927Application Date: 2001-11-07
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Publication No.: US06642252B2Publication Date: 2003-11-04
- Inventor: Gregory S. Bisacchi , James C. Sutton , William A. Slusarchyk , Uwe D. Treuner , Guohua Zhao , Daniel L. Cheney , Yan Shi , Shung C. Wu
- Applicant: Gregory S. Bisacchi , James C. Sutton , William A. Slusarchyk , Uwe D. Treuner , Guohua Zhao , Daniel L. Cheney , Yan Shi , Shung C. Wu
- Main IPC: C07D40102
- IPC: C07D40102
Abstract:
Compounds having the formula (I), are useful as serine protease inhibitors, more particularly inhibitors of Factors VIIa, IXa, Xa, and/or XIa, wherein ring B is phenyl or pyridyl, W is preferably C(═O)NR4R5, L is a linker group, X2 comprises nitrogen or carbon, Z is an optionally-substituted monocyclic or bicyclic ring system, and R1, R2, R3, R4, R5 and R6 are as defined in the specification.
Public/Granted literature
- US20030166685A1 Acid derivatives useful as serine protease inhibitors Public/Granted day:2003-09-04
Information query
