A microdermabrasion handpiece includes a supply lumen and a return lumen in fluid communication with an abrasion chamber. A window formed at a distal end of the handpiece is off-centered from the supply lumen. The supply lumen directs a flow of abrasive particulate in a first direction. A supply nozzle adjacent to the distal end of the handpiece directs the flow of abrasive particulate at the window in a second direction different from the first direction. Methods for performing microdermabrasion are also provided.