Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors

发明授权

US06696477B2 Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors 失效

标题翻译：杂环取代的异羟肟酸衍生物作为环加氧酶-2和5-脂氧合酶抑制剂

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专利标题： Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
专利标题（中）： 杂环取代的异羟肟酸衍生物作为环加氧酶-2和5-脂氧合酶抑制剂
申请号： US09997633

申请日： 2001-11-29
公开(公告)号： US06696477B2

公开(公告)日： 2004-02-24
发明人: John J. Talley , James A. Sikorski , Matthew J. Graneto , Jeffery S. Carter , Bryan H. Norman , Balekudru Devadas
申请人： John J. Talley , James A. Sikorski , Matthew J. Graneto , Jeffery S. Carter , Bryan H. Norman , Balekudru Devadas
主分类号： C07D23110
IPC分类号： C07D23110

Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors

摘要：

This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation. Compounds of particular interest are defined by Formula I wherein A, Y, R1, R2, R3, R4 and R5 are as defined in the specification.

摘要（中）：

本发明涉及抗炎药物领域，具体涉及用于治疗由环氧合酶-2或5-脂氧合酶如炎症介导的病症的化合物，组合物和方法。特别感兴趣的化合物由式I定义，其中A，Y，R 1，R 2，R 3，R 4和R 5如说明书中所定义。

公开/授权文献

US20020058810A1 Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors 公开/授权日：2002-05-16

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