- 专利标题： Skin and muscle-targeted gene therapy by pulsed electrical field
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申请号： US09352809申请日： 1999-07-13
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公开(公告)号： US06697669B2公开(公告)日： 2004-02-24
- 发明人: Nagendu B. Dev , Gunter A. Hofmann , Edward Nolan , Dietmar P. Rabussay , Arnt Tonnessen , Georg Widera , Lei Zhang
- 申请人： Nagendu B. Dev , Gunter A. Hofmann , Edward Nolan , Dietmar P. Rabussay , Arnt Tonnessen , Georg Widera , Lei Zhang
- 主分类号： A61N130
- IPC分类号： A61N130
摘要：
The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.
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