Invention Grant
- Patent Title: N-acylsulfonamide apoptosis promoters
- Patent Title (中): N-酰基磺酰胺凋亡启动子
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Application No.: US09957276Application Date: 2001-09-20
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Publication No.: US06720338B2Publication Date: 2004-04-13
- Inventor: David J. Augeri , Steven A. Baumeister , Milan Bruncko , Daniel A. Dickman , Hong Ding , Jurgen Dinges , Stephen W. Fesik , Philip J. Hajduk , Aaron R. Kunzer , William McClellan , David G. Nettesheim , Thorsten Oost , Andrew M. Petros , Saul H. Rosenberg , Wang Shen , Sheela A. Thomas , Xilu Wang , Michael D. Wendt
- Applicant: David J. Augeri , Steven A. Baumeister , Milan Bruncko , Daniel A. Dickman , Hong Ding , Jurgen Dinges , Stephen W. Fesik , Philip J. Hajduk , Aaron R. Kunzer , William McClellan , David G. Nettesheim , Thorsten Oost , Andrew M. Petros , Saul H. Rosenberg , Wang Shen , Sheela A. Thomas , Xilu Wang , Michael D. Wendt
- Main IPC: A61K31445
- IPC: A61K31445
Abstract:
N-Benzoyl arylsulfonamides having the formula: are BCL-X1 inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-X1 inhibiting compositions and methods of promoting apoptosis in a mammal.
Public/Granted literature
- US20020086887A1 N-Acylsulfonamide apoptosis promoters Public/Granted day:2002-07-04
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