Invention Grant
US06797818B2 Methods for labeling nucleotides, labeled nucleotides and useful intermediates
有权
标记核苷酸，标记核苷酸和有用中间体的方法
- Patent Title: Methods for labeling nucleotides, labeled nucleotides and useful intermediates
- Patent Title (中): 标记核苷酸，标记核苷酸和有用中间体的方法
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Application No.: US10047874Application Date: 2002-01-14
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Publication No.: US06797818B2Publication Date: 2004-09-28
- Inventor: Hendrick Jan Houthoff , Jan Reedijk , Tinka Jelsma , Robert Jochem Heetebrij , Herman Hendricus Volkers
- Applicant: Hendrick Jan Houthoff , Jan Reedijk , Tinka Jelsma , Robert Jochem Heetebrij , Herman Hendricus Volkers
- Priority: EP96202792 19961008; WOPCT/NL97/00559 19971008
- Main IPC: C07H2102
- IPC: C07H2102
Abstract:
The present invention provides a labeled nucleotide having formula: where X is an aliphatic diamine, and the labeling moiety comprises a label and a spacer, where the spacer is coupled at one end to a platinum atom and at the other end to the label, which spacer comprises a chain having at least four atoms. The invention further provides a method for labeling a nucleotide, kits for labeling a nucleotide, and kits containing labeled nucleotides.
Public/Granted literature
- US20020160396A1 Methods for labeling nucleotides, labeled nucleotides and useful intermediates Public/Granted day:2002-10-31
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