发明授权
- 专利标题: &agr;-glycated amino acid releasing enzyme
- 专利标题(中): α-糖基化氨基酸释放酶
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申请号: US09958515申请日: 2001-10-09
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公开(公告)号: US06825016B1公开(公告)日: 2004-11-30
- 发明人: Kaori Ishimaru , Masayuki Yagi , Satoshi Yonehara
- 申请人: Kaori Ishimaru , Masayuki Yagi , Satoshi Yonehara
- 优先权: JP11-142185 19990412
- 主分类号: C12N900
- IPC分类号: C12N900
摘要:
The present invention relates to a novel enzyme (&agr;-GARE) which releases an amino acid residue having a glycated &agr;-amino group (&agr;-GA) from a glycated protein etc. and to bacterial strains producing the same. Examples of the bacterial strains include Sphingomonas parapaucimobilis KDK1004 (FERM BP-7041). The &agr;-GARE is contained in the culture supernatant of this strain and &agr;-GA can be released from a glycated peptide by using the same, as shown in FIG. 1.
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