发明授权
- 专利标题: Control of process humidity to produce large, porous particles
- 专利标题(中): 控制工艺湿度以产生大的多孔颗粒
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申请号: US09837620申请日: 2001-04-18
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公开(公告)号: US06848197B2公开(公告)日: 2005-02-01
- 发明人: Donghao Chen , Richard P. Batycky , Lloyd Johnston , Jeffrey Mintzes
- 申请人: Donghao Chen , Richard P. Batycky , Lloyd Johnston , Jeffrey Mintzes
- 申请人地址: US MA Cambridge US PA University Park
- 专利权人: Advanced Inhalation Research, Inc.,The Penn State Research Foundation, Inc.
- 当前专利权人: Advanced Inhalation Research, Inc.,The Penn State Research Foundation, Inc.
- 当前专利权人地址: US MA Cambridge US PA University Park
- 代理机构: Elmore Craig, PC
- 代理商 Anne I. Craig; Carolyn S. Elmore
- 主分类号: A61K9/72
- IPC分类号: A61K9/72 ; A61K9/00 ; A61K9/14 ; A61K9/16 ; A61K47/24 ; A61L9/04 ; B05D7/00 ; E02F5/10 ; A01N25/02
摘要:
Spray dried particles having specified aerodynamic characteristics are produced by atomizing a liquid feed and contacting the liquid feed with a drying gas, such as, for example, air or nitrogen. The humidity of the drying gas is controlled to a value, expressed, for instance, as dew point, which is known to produce particles having a specified tap density or aerodynamic diameter. Particles having a volume median geometric diameter greater than about 5 microns and a tap density less than about 0.4 g/cm3 are preferred.
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