发明授权
- 专利标题： Methods and interferon deficient substrates for the propagation of viruses
- 专利标题（中）： 用于病毒传播的方法和干扰素缺陷底物
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申请号： US09724419申请日： 2000-11-28
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公开(公告)号： US06852522B1公开(公告)日： 2005-02-08
- 发明人: Peter Palese , Adolfo Garcia-Sastre , Robert O'Neil
- 申请人： Peter Palese , Adolfo Garcia-Sastre , Robert O'Neil
- 申请人地址： US NY New York
- 专利权人： Mount Sinai School of Medicine of New York University
- 当前专利权人： Mount Sinai School of Medicine of New York University
- 当前专利权人地址： US NY New York
- 代理机构： Jones Day
- 主分类号： C12N15/01
- IPC分类号： C12N15/01 ; A61K35/76 ; A61K39/00 ; A61K39/12 ; A61K39/145 ; A61K39/155 ; A61K39/17 ; A61K39/205 ; A61K45/00 ; A61P31/12 ; A61P31/14 ; A61P31/16 ; A61P35/00 ; A61P37/02 ; C07K14/11 ; C12N7/00 ; C12N7/01 ; C12N7/04 ; C12N15/09 ; C12N15/86
摘要：
The present invention relates, to novel methods and substrates for the propagation of viruses. The invention relates to IFN-deficient substrates and methods for propagating viruses in these unconventional substrates. In particular, the invention relates to methods of propagating viruses in immature embryonated eggs, preferably six- to nine-day-old chicken eggs. The methods of the invention are particularly attractive for growing viruses suitable for use in vaccine and pharmaceutical formulations.
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