发明授权
US06858407B2 Human leucine-rich repeat containing protein expressed predominately in small intestine, HLRRSI1
有权
人类富含亮氨酸的重复含有蛋白主要表达于小肠，HLRRSI1
- 专利标题： Human leucine-rich repeat containing protein expressed predominately in small intestine, HLRRSI1
- 专利标题（中）： 人类富含亮氨酸的重复含有蛋白主要表达于小肠，HLRRSI1
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申请号： US10029347申请日： 2001-12-20
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公开(公告)号： US06858407B2公开(公告)日： 2005-02-22
- 发明人: John N. Feder , Chandra S. Ramanathan , Gabriel A. Mintier
- 申请人： John N. Feder , Chandra S. Ramanathan , Gabriel A. Mintier
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Stephen C. D'Amico
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K39/395 ; A61K48/00 ; A61P1/00 ; A61P9/04 ; A61P9/10 ; A61P31/18 ; A61P35/00 ; A61P37/00 ; A61P43/00 ; C07K14/47 ; C07K14/705 ; C07K16/18 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/02 ; C12N5/10 ; C12N15/09 ; C12N15/12 ; C12P21/02 ; C12Q1/68 ; G01N33/68 ; C12P21/06 ; C07H21/04
摘要：
The present invention provides novel polynucleotides encoding HLRRSI1 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HLRRSI1 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly gastrointestinal diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
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