发明授权
- 专利标题: Heteroaromatic bicyclic derivatives useful as anticancer agents
- 专利标题(中): 用作抗癌剂的杂芳族双环衍生物
-
申请号: US10226255申请日: 2002-08-22
-
公开(公告)号: US06867201B2公开(公告)日: 2005-03-15
- 发明人: John Charles Kath , Norma Jacqueline Tom , Eric David Cox , Samit Kumar Bhattacharya
- 申请人: John Charles Kath , Norma Jacqueline Tom , Eric David Cox , Samit Kumar Bhattacharya
- 申请人地址: US NY New York
- 专利权人: Pfizer Inc
- 当前专利权人: Pfizer Inc
- 当前专利权人地址: US NY New York
- 代理商 Peter C. Richardson; Garth Butterfield; Pamela C. Ancona
- 主分类号: A61K31/437
- IPC分类号: A61K31/437 ; A61K31/4375 ; A61K31/439 ; A61K31/46 ; A61K31/517 ; A61K31/519 ; A61K45/06 ; A61P35/00 ; C07D239/94 ; C07D401/10 ; C07D403/10 ; C07D403/14 ; C07D405/12 ; C07D417/14 ; C07D451/02 ; C07D451/04 ; C07D451/06 ; C07D453/02 ; C07D471/04 ; A61K31/33 ; C07D239/00 ; C07D239/70 ; C07D403/00
摘要:
The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3 and R4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
公开/授权文献
信息查询
IPC分类: