发明授权
US06869788B2 DNA encoding novel D-aminoacylase and process for producing D-amino acid by using the same
失效
编码新型D-氨基酸酰基酶的DNA和使用它们生产D-氨基酸的方法
- 专利标题： DNA encoding novel D-aminoacylase and process for producing D-amino acid by using the same
- 专利标题（中）： 编码新型D-氨基酸酰基酶的DNA和使用它们生产D-氨基酸的方法
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申请号： US10240422申请日： 2002-02-01
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公开(公告)号： US06869788B2公开(公告)日： 2005-03-22
- 发明人: Masami Osabe , Katsuyuki Takahashi , Toshifumi Yamaki , Teruo Arii , Toshihiro Oikawa
- 申请人： Masami Osabe , Katsuyuki Takahashi , Toshifumi Yamaki , Teruo Arii , Toshihiro Oikawa
- 申请人地址： JP Tokyo
- 专利权人： Mitsui Chemicals, Inc.
- 当前专利权人： Mitsui Chemicals, Inc.
- 当前专利权人地址： JP Tokyo
- 代理机构： Burns, Doane, Swecker & Mathis, L.L.P.
- 优先权： JP2001-024986 20010201
- 国际申请： PCTJP02/00853 WO 20020201
- 国际公布： WO0206107 WO 20020808
- 主分类号： C12N1/21
- IPC分类号： C12N1/21 ; C12N9/80 ; C12P13/04 ; C12P41/00 ; C12N9/78 ; C07H21/04 ; C07K17/00 ; C12P13/22 ; C12Q1/34
摘要：
This invention provides a novel D-aminoacylase obtained by cloning a DNA encoding the novel D-aminoacylase from Methylobacterium mesophilicum MT 10894, etc. and which shows sufficiently high activity at an industrially useful substrate concentration to allow a D-amino acid to be efficiently produced from an N-acyl-DL-amino acid; a DNA encoding the D-aminoacylase; a process for producing a D-amino acid from the corresponding N-acylamino acid using a transformant containing the DNA.
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