Invention Grant
- Patent Title: Urea derivatives as inhibitors for CCR-3 receptor
- Patent Title (中): 尿素衍生物作为CCR-3受体的抑制剂
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Application No.: US10019652Application Date: 2000-07-28
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Publication No.: US06875884B1Publication Date: 2005-04-05
- Inventor: Janak Padia , Michael Hocker , Tsuyoshi Nishitoba , Hirohi Ohashi , Eiji Sawa
- Applicant: Janak Padia , Michael Hocker , Tsuyoshi Nishitoba , Hirohi Ohashi , Eiji Sawa
- Applicant Address: JP Tokyo
- Assignee: Kirin Beer Kabushiki Kaisha
- Current Assignee: Kirin Beer Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- International Application: PCTUS00/17868 WO 20000728
- International Announcement: WO0109088 WO 20010208
- Main IPC: C07C275/28
- IPC: C07C275/28 ; C07C275/30 ; C07C275/38 ; C07C275/42 ; C07C323/25 ; C07C335/16 ; C07D207/09 ; C07D209/16 ; C07D213/38 ; C07D213/75 ; C07D215/12 ; C07D233/54 ; C07D233/61 ; C07D257/04 ; C07D277/66 ; C07D307/52 ; C07D307/68 ; C07D317/58 ; C07D333/20 ; C07C205/00 ; C07C229/00 ; C07C327/00 ; C07D215/38
Abstract:
Urea and thiourea derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful urea and thiourea derivatives can be synthesized using liquid and solid phase synthesis protocols.
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