- 专利标题: Substituted alkylamine derivatives and methods of use
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申请号: US10197974申请日: 2002-07-17
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公开(公告)号: US06878714B2公开(公告)日: 2005-04-12
- 发明人: Benny Askew , Jeffrey Adams , Shon Booker , Guoqing Chen , Lucian V. DiPietro , Daniel Elbaum , Julie Germain , Stephanie D. Geuns-Meyer , Gregory J. Habgood , Michael Handley , Qi Huang , Tae-Seong Kim , Aiwen Li , Nobuko Nishimura , Rana Nomak , Vinod F. Patel , Babak Riahi , Joseph L. Kim , Ning Xi , Kevin Yang , Chester Chenguang Yuan
- 申请人: Benny Askew , Jeffrey Adams , Shon Booker , Guoqing Chen , Lucian V. DiPietro , Daniel Elbaum , Julie Germain , Stephanie D. Geuns-Meyer , Gregory J. Habgood , Michael Handley , Qi Huang , Tae-Seong Kim , Aiwen Li , Nobuko Nishimura , Rana Nomak , Vinod F. Patel , Babak Riahi , Joseph L. Kim , Ning Xi , Kevin Yang , Chester Chenguang Yuan
- 申请人地址: US CA Thousand Oaks
- 专利权人: Amgen Inc.
- 当前专利权人: Amgen Inc.
- 当前专利权人地址: US CA Thousand Oaks
- 代理商 Joseph W. Bulock
- 主分类号: A61K31/4436
- IPC分类号: A61K31/4436 ; A61K31/4439 ; A61K31/444 ; A61K31/4709 ; A61K31/496 ; A61K31/501 ; A61K31/506 ; A61K31/5377 ; A61P9/10 ; A61P11/06 ; A61P15/08 ; A61P17/06 ; A61P19/00 ; A61P27/02 ; A61P29/00 ; A61P35/00 ; A61P43/00 ; C07D213/82 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D405/14 ; C07D407/14 ; C07D409/04 ; C07D409/12 ; C07D409/14 ; C07D413/14 ; C07D417/14 ; C07D471/02 ; C07D471/04 ; C07D491/02 ; A61K31/4427
摘要:
Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
公开/授权文献
- US20030225106A1 Substituted alkylamine derivatives and methods of use 公开/授权日:2003-12-04
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