发明授权
- 专利标题： Methods of screening for ulcerative colitis and crohn's disease
- 专利标题（中）： 筛查溃疡性结肠炎和克罗恩病的方法
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申请号： US09419408申请日： 1999-10-15
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公开(公告)号： US06884590B1公开(公告)日： 2005-04-26
- 发明人: Jerome I. Rotter , Stephan R. Targan , Huiying Yang , Arthur L. Beaudet , Devendra Vora
- 申请人： Jerome I. Rotter , Stephan R. Targan , Huiying Yang , Arthur L. Beaudet , Devendra Vora
- 申请人地址： US CA Los Angeles
- 专利权人： Cedars-Sinai Medical Center
- 当前专利权人： Cedars-Sinai Medical Center
- 当前专利权人地址： US CA Los Angeles
- 代理机构： McDermott, Will & Emery
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C07K16/28 ; C12Q1/68 ; G01N33/53
摘要：
A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by, R241 allele and kits which exploit the inventive methods.
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