发明授权
- 专利标题: Pyrido[2,1-a]isoquinoline derivatives
- 专利标题(中): 吡啶并[2,1-a]异喹啉衍生物
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申请号: US10800991申请日: 2004-03-15
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公开(公告)号: US06897222B2公开(公告)日: 2005-05-24
- 发明人: Luca Claudio Gobbi , Thomas Luebbers , Patrizio Mattei , Robert Narquizian , Pierre Charles Wyss
- 申请人: Luca Claudio Gobbi , Thomas Luebbers , Patrizio Mattei , Robert Narquizian , Pierre Charles Wyss
- 申请人地址: US NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Nutley
- 代理商 George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- 优先权: EP01130882 20011227
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/445 ; A61K31/4738 ; A61P1/04 ; A61P3/04 ; A61P3/10 ; A61P7/10 ; A61P9/12 ; C07D455/06 ; A61K31/4745 ; C07D471/02
摘要:
The present invention provides compounds of formula (I): wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
公开/授权文献
- US20040176406A1 Pyrido [2,1-a] isoquinoline derivatives 公开/授权日:2004-09-09
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