Invention Grant
- Patent Title: Substituted azepino[4,5b]indole derivatives
- Patent Title (中): 取代的azepino [4,5b]吲哚衍生物
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Application No.: US10393968Application Date: 2003-03-20
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Publication No.: US06903090B2Publication Date: 2005-06-07
- Inventor: Kristine E. Frank , Brad A. Acker , Michael D. Ennis , Jed F. Fisher , Jian-min Fu , William W. McWhorter, Jr. , Jeanette K. Morris , Donald Joseph Rogier , Eric Jon Jacobsen
- Applicant: Kristine E. Frank , Brad A. Acker , Michael D. Ennis , Jed F. Fisher , Jian-min Fu , William W. McWhorter, Jr. , Jeanette K. Morris , Donald Joseph Rogier , Eric Jon Jacobsen
- Applicant Address: US NJ Bridgewater
- Assignee: Pfizer
- Current Assignee: Pfizer
- Current Assignee Address: US NJ Bridgewater
- Agency: Schwegman, Lundberg, Woessner & Kluth, P.A.
- Main IPC: A61K31/55
- IPC: A61K31/55 ; A61P3/04 ; A61P25/00 ; A61P25/02 ; A61P25/06 ; A61P25/08 ; A61P25/14 ; A61P25/16 ; A61P25/18 ; A61P25/20 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; A61P25/30 ; A61P43/00 ; C07D487/04 ; G06T3/00
![Substituted azepino[4,5b]indole derivatives](/abs-image/US/2005/06/07/US06903090B2/abs.jpg.150x150.jpg)
Abstract:
Disclosed are compounds of Formula (I): wherein R1-R4, p and q have any of the values described in the specification, as well as pharmaceutical salts thereof, and pharmaceutical compositions containing such compounds or salts. The compounds and salts are 5-HT ligands and are useful for treating diseases, disorders, and/or conditions in a mammal wherein activity of a 5-HT receptor is implicated. The compounds and salts are particularly useful for treating diseases of the central nervous system.
Public/Granted literature
- US20030220321A1 Substituted azepino[4,5b]indole derivatives Public/Granted day:2003-11-27
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