发明授权
- 专利标题: High throughput ion source for MALDI mass spectrometry
- 专利标题(中): MALDI质谱仪的高通量离子源
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申请号: US10804849申请日: 2004-03-19
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公开(公告)号: US06903334B1公开(公告)日: 2005-06-07
- 发明人: Alexander A. Makarov , Anatoli V. Verentchikov
- 申请人: Alexander A. Makarov , Anatoli V. Verentchikov
- 申请人地址: US CA San Jose
- 专利权人: Thermo Finnigan LLC
- 当前专利权人: Thermo Finnigan LLC
- 当前专利权人地址: US CA San Jose
- 代理机构: Fish & Richardson P.C.
- 代理商 Sharon Upham
- 主分类号: H01J49/04
- IPC分类号: H01J49/04 ; H01J49/16 ; H01J49/40 ; H01J49/42
摘要:
Mass spectrometers, ion sources and methods for providing and transporting analyte ions derived from a sample to ion optics. A sample chamber is configured to receive a sample plate supporting a sample, and an illumination source is configured to illuminate the sample to generate analyte ions and particles. A matrix-protecting interface is located between the sample plate and the ion optics, and configured such that the shortest travel path between the illuminated portion of the sample plate and the sampling aperture or input of the ion optics is substantially obstructed. Alternatively, a gas flow directed at an angle from zero to 90 degrees relative to the main axis of the ion optics and away from the ion optics influences particles generated by the action of the illumination source away from the ion optics, and a voltage source extracts analyte ions of interest.
公开/授权文献
- US2587210A Production of acrylamides 公开/授权日:1952-02-26