发明授权
- 专利标题: Photoreduction method for hemoglobin-vesicle
- 专利标题(中): 血红蛋白囊泡光还原法
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申请号: US10073084申请日: 2002-02-12
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公开(公告)号: US06916303B2公开(公告)日: 2005-07-12
- 发明人: Eishun Tsuchida , Hiromi Sakai , Hiroto Onuma , Shinji Takeoka
- 申请人: Eishun Tsuchida , Hiromi Sakai , Hiroto Onuma , Shinji Takeoka
- 申请人地址: JP Kawaguchi
- 专利权人: Japan Science and Technology Corporation
- 当前专利权人: Japan Science and Technology Corporation
- 当前专利权人地址: JP Kawaguchi
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权: JP2000-175611 20000612
- 主分类号: A61K9/08
- IPC分类号: A61K9/08 ; A61K31/045 ; A61K31/198 ; A61K31/525 ; A61K31/7004 ; A61K31/7016 ; A61K38/16 ; A61K38/42 ; A61K47/10 ; A61K47/18 ; A61K47/22 ; A61K47/26 ; A61K47/48 ; A61M1/36 ; A61P7/00 ; A61P9/00 ; A61M37/00
摘要:
A method and an apparatus for regenerating an oxygen-binding ability by reducing the methemoglobin contained in hemoglobin-vesicle by light irradiation. This method includes adding electron donors such as amino acids, saccharides, alcohols, and/or flavin derivatives in appropriate amounts to the inner aqueous phase of the hemoglobin-vesicle, applying light to the vesicle when the content of methemoglobin increases as a result of oxidation of hemoglobin, thereby reducing the metohemoglobin. In this manner, the oxygen-binding ability is recovered, thereby maintaining the function of the hemoglobin-vesicle.
公开/授权文献
- US20020095108A1 Photoreduction method for hemoglobin-visicle 公开/授权日:2002-07-18