发明授权
- 专利标题： Prolonged release bioadhesive therapeutic systems
- 专利标题（中）： 长期释放生物粘附治疗系统
-
申请号： US10307938申请日： 2002-12-03
-
公开(公告)号： US06916485B2公开(公告)日： 2005-07-12
- 发明人: Jean-Marc Aiache , Dominique Costantini , Christine Chaumont
- 申请人： Jean-Marc Aiache , Dominique Costantini , Christine Chaumont
- 申请人地址： FR Paris
- 专利权人： Bioalliance Pharma
- 当前专利权人： Bioalliance Pharma
- 当前专利权人地址： FR Paris
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP.
- 优先权： FR0109811 20010723
- 主分类号： A61K9/70
- IPC分类号： A61K9/70 ; A61K9/00 ; A61K9/20 ; A61K9/22 ; A61K31/4174 ; A61K31/4468 ; A61K31/7048 ; A61K31/7064 ; A61K47/20 ; A61K47/26 ; A61K47/36 ; A61K47/42 ; A61P1/02 ; A61P13/00 ; A61P17/00 ; A61P25/04 ; A61P29/00 ; A61P29/02 ; A61P31/00 ; A61P31/04 ; A61P31/10 ; A61P31/14 ; A61P31/18 ; A61P35/00 ; A61F6/06 ; A61F13/00 ; A61K47/00
摘要：
The present invention concerns a prolonged release bioadhesive mucosal therapeutic system containing at least one active principle, with an active dissolution test of more than 70% over 8 hours and to a method for its preparation. The bioadhesive therapeutic system may be in tablet form and may contain quantities of natural proteins representing at least 50% by weight of active principle and at least 20% by weight of the tablet, between 10% and 20% of a hydrophilic polymer, and compression excipients, and may contain between 4% and 10% of an alkali metal alkylsulphate to reinforce the local availability of active principle and between 0.1% and 1% of a monohydrate sugar.
公开/授权文献
- US20030108603A1 Prolonged release bioadhesive therapeutic systems 公开/授权日：2003-06-12