发明授权
- 专利标题： Heterocyclic derivatives, preparation method and pharmaceutical compositions containing same
- 专利标题（中）： 杂环衍生物，制备方法和含有它们的药物组合物
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申请号： US10203113申请日： 2001-02-01
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公开(公告)号： US06919362B2公开(公告)日： 2005-07-19
- 发明人: Daniel Lesieur , Elodie Blanc-Delmas , Said Yous , Patrick Depreux , Gérald Guillaumet , Catherine Dacquet , Nigel Levens , Jean Albert Boutin , Caroline Bennejean , Pierre Renard
- 申请人： Daniel Lesieur , Elodie Blanc-Delmas , Said Yous , Patrick Depreux , Gérald Guillaumet , Catherine Dacquet , Nigel Levens , Jean Albert Boutin , Caroline Bennejean , Pierre Renard
- 申请人地址： FR Courbevoie
- 专利权人： Les Laboratoires Servier
- 当前专利权人： Les Laboratoires Servier
- 当前专利权人地址： FR Courbevoie
- 代理机构： The Firm of Hueschen and Sage
- 优先权： FR0001289 20000202
- 国际申请： PCT/FR01/00304 WO 20010201
- 国际公布： WO01/57002 WO 20010809
- 主分类号： A61K31/423
- IPC分类号： A61K31/423 ; A61K31/428 ; A61K31/437 ; A61K31/4439 ; A61P1/00 ; A61P1/04 ; A61P1/14 ; A61P1/18 ; A61P3/04 ; A61P3/06 ; A61P3/10 ; A61P5/00 ; A61P9/00 ; A61P9/10 ; A61P9/14 ; A61P13/00 ; A61P13/12 ; A61P15/00 ; A61P17/06 ; A61P19/10 ; A61P21/00 ; A61P21/04 ; A61P25/28 ; A61P35/00 ; A61P43/00 ; C07B61/00 ; C07D263/58 ; C07D277/68 ; C07D417/06 ; C07D471/04 ; C07D498/04
摘要：
Compounds of formula (I): wherein: X represents an oxygen or a sulphur or CH2 or R1 and R2 represent a hydrogen atom, or a group as defined in the description, A represents an alkylene chain as described in the description, B is as defined in the description, R3 and R4 represent a hydrogen atom or a group as defined in the description, D represents an optionally substituted benzene, optionally substituted pyrazine, optionally substituted pyrimidine or optionally substituted pyridazine and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
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