- 专利标题： Nucleic acid ligands to the prostate specific membrane antigen
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申请号： US09978969申请日： 2001-10-16
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公开(公告)号： US06933114B2公开(公告)日： 2005-08-23
- 发明人: Shawn E. Lupold , Yun Lin , Brian J. Hicke , Donald S. Coffey
- 申请人： Shawn E. Lupold , Yun Lin , Brian J. Hicke , Donald S. Coffey
- 申请人地址： US CA Foster City
- 专利权人： Gilead Sciences, Inc.
- 当前专利权人： Gilead Sciences, Inc.
- 当前专利权人地址： US CA Foster City
- 代理机构： Swanson & Bratschun, LLC
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K47/48 ; A61K51/00 ; A61P35/00 ; C07K14/705 ; C07K17/02 ; C12N15/115 ; C12Q1/68 ; C07H21/04 ; C12N14/00
摘要：
Methods are provided for generating nucleic acid ligands of Prostate Specific Membrane Antigen (PSMA). The methods of the invention use the SELEX method for the isolation of nucleic acid ligands. The invention also includes nucleic acid ligands to PSMA, and methods and compositions for the treatment and diagnosis of disease using the nucleic acid ligands.
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