发明授权
- 专利标题： Heterocyclic compounds as ligands of the GABAA receptor
- 专利标题（中）： 杂环化合物作为GABA A受体的配体
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申请号： US10670077申请日： 2003-09-23
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公开(公告)号： US06949562B2公开(公告)日： 2005-09-27
- 发明人: Daniel Yohannes , George Maynard , Jun Yuan , Linghong Xie , Kyungae Lee , Manuka Ghosh , George Luke , Xiaojun Liu , Arthur Nagal , Lawrence Vincent , Kevin Currie , Zhe-Quing Wang
- 申请人： Daniel Yohannes , George Maynard , Jun Yuan , Linghong Xie , Kyungae Lee , Manuka Ghosh , George Luke , Xiaojun Liu , Arthur Nagal , Lawrence Vincent , Kevin Currie , Zhe-Quing Wang
- 申请人地址： US CT Branford US NY New York
- 专利权人： Neurogen Corporation,Pfizer, Inc.
- 当前专利权人： Neurogen Corporation,Pfizer, Inc.
- 当前专利权人地址： US CT Branford US NY New York
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： A61K31/4162
- IPC分类号： A61K31/4162 ; A61K31/4178 ; A61K31/4188 ; A61K31/429 ; A61K31/437 ; A61K31/4375 ; A61K31/444 ; A61K31/4709 ; A61K31/4745 ; A61K31/497 ; A61K31/506 ; A61K31/519 ; A61K31/5377 ; A61P25/00 ; A61P25/20 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; A61P43/00 ; C07D403/04 ; C07D471/04 ; C07D471/14 ; C07D487/04 ; C07D487/14 ; C07D498/04 ; C07D513/04 ; A61K31/4353
摘要：
Disclosed are heterocyclic compounds of the formula and the pharmaceutically acceptable salts thereof wherein the variables A, V, Y, J, E, X, T, G, Q, W, Z, b, n and m are defined herein. These compounds are highly selective agonists, antagonists or inverse agonists for GABAA brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAA brain receptor.
公开/授权文献
- US20040110778A1 Heterocyclic compounds as ligands of the GABAA receptor 公开/授权日：2004-06-10
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