Invention Grant
US06973741B2 Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
有权
使用改进的喷雾干燥装置制备均匀喷雾干燥的固体无定形药物分散体的方法
- Patent Title: Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
- Patent Title (中): 使用改进的喷雾干燥装置制备均匀喷雾干燥的固体无定形药物分散体的方法
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Application No.: US10766450Application Date: 2004-01-27
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Publication No.: US06973741B2Publication Date: 2005-12-13
- Inventor: Ronald A. Beyerinck , Heather L. M. Diebele , Dan E. Dobry , Roderick J. Ray , Dana M. Settell , Ken R. Spence
- Applicant: Ronald A. Beyerinck , Heather L. M. Diebele , Dan E. Dobry , Roderick J. Ray , Dana M. Settell , Ken R. Spence
- Applicant Address: US NY New York
- Assignee: Pfizer, Inc.
- Current Assignee: Pfizer, Inc.
- Current Assignee Address: US NY New York
- Agent Gregg C. Benson; Lisa A. Samuels
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/16 ; A61K31/404 ; A61K31/47 ; A61K47/32 ; A61K47/38 ; A61P43/00 ; F26B3/12
Abstract:
Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
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