![Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses](/docs/US/2005-12-13/US06974870B2/abs.jpg.600x600.jpg)
- 专利标题： Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
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申请号： US10730172申请日： 2003-12-06
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公开(公告)号： US06974870B2公开(公告)日： 2005-12-13
- 发明人: Charles L. Cywin , Can Mao , Jonathan Emeigh , Roman Wolfgang Fleck , Ming-Hong Hao , Eugene Hickey , Weimin Liu , Daniel Richard Marshall , Tina Morwick , Peter Nemoto , Ronald John Sorcek , Sanxing Sun , Jiang-Ping Wu , Erick Young , Darren DiSalvo , John Ginn , Pier Cirillo
- 申请人： Charles L. Cywin , Can Mao , Jonathan Emeigh , Roman Wolfgang Fleck , Ming-Hong Hao , Eugene Hickey , Weimin Liu , Daniel Richard Marshall , Tina Morwick , Peter Nemoto , Ronald John Sorcek , Sanxing Sun , Jiang-Ping Wu , Erick Young , Darren DiSalvo , John Ginn , Pier Cirillo
- 申请人地址： US CT Ridgefield
- 专利权人： Boehringer Ingelheim Phamaceuticals, Inc.
- 当前专利权人： Boehringer Ingelheim Phamaceuticals, Inc.
- 当前专利权人地址： US CT Ridgefield
- 代理商 Michael Morris; Mary-Ellen Devlin; David A. Dow
- 主分类号： A61K31/38
- IPC分类号： A61K31/38 ; A61K31/435 ; C07D495/04 ; A61K31/4365 ; A61K31/497 ; A61K31/5377
![Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses](/abs-image/US/2005/12/13/US06974870B2/abs.jpg.150x150.jpg)
摘要：
Disclosed are compounds of formula (I): wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
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