- 专利标题： Gene involved in CADASIL, method of diagnosis and therapeutic application
-
申请号： US09612226申请日： 2000-07-07
-
公开(公告)号： US06995257B1公开(公告)日： 2006-02-07
- 发明人: Elisabeth Tournier-Lasserve , Anne Joutel , Marie-Germaine Bousser , Jean-François Bach
- 申请人： Elisabeth Tournier-Lasserve , Anne Joutel , Marie-Germaine Bousser , Jean-François Bach
- 申请人地址： FR Paris FR Paris
- 专利权人： Institut National de la Santa et de la Recherche (INSERM),Assistance Publique - Hopitaux de Paris
- 当前专利权人： Institut National de la Santa et de la Recherche (INSERM),Assistance Publique - Hopitaux de Paris
- 当前专利权人地址： FR Paris FR Paris
- 代理机构： Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 优先权： FR9609733 19960801; FR9704680 19970416
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C07H21/02 ; G01N33/567 ; G01N33/566 ; C12Q1/68
摘要：
The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
信息查询
