发明授权
- 专利标题： Compositions and methods for therapeutic use
- 专利标题（中）： 用于治疗用途的组合物和方法
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申请号： US08889355申请日： 1997-07-08
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公开(公告)号： US07002027B1公开(公告)日： 2006-02-21
- 发明人: Heidrun Engler , Tattanahalli L. Nagabhushan , Stephen Kenneth Youngster
- 申请人： Heidrun Engler , Tattanahalli L. Nagabhushan , Stephen Kenneth Youngster
- 申请人地址： US NJ Kenilworth US NJ Kenilworth
- 专利权人： Canji, Inc.,Schering Corporation
- 当前专利权人： Canji, Inc.,Schering Corporation
- 当前专利权人地址： US NJ Kenilworth US NJ Kenilworth
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： C07J9/00
- IPC分类号： C07J9/00 ; C07H1/00
摘要：
The present invention is directed to compositions and methods of treating cancer by gene therapy using a therapeutic gene formulated in a buffer comprising a delivery-enhancing agent. The delivery-enhancing agents of the invention can be used to formulate therapeutic or diagnostic agents, such as proteins, nucleic acids, antisense RNA, small molecules, etc., for administration to any tissue or organ having an epithelial membrane. The delivery-enhancing agents include detergents, alcohols, surfactants and other molecules.
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