- 专利标题: Male contraceptive formulation comprising norethisterone
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申请号: US09764149申请日: 2001-01-19
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公开(公告)号: US07025979B2公开(公告)日: 2006-04-11
- 发明人: Eberhard Nieschlag , Axel Kamischke , Michael Oettel , Alexander Ruebig , Ekkerhard Schillinger , Ursula-Friederike Habenicht
- 申请人: Eberhard Nieschlag , Axel Kamischke , Michael Oettel , Alexander Ruebig , Ekkerhard Schillinger , Ursula-Friederike Habenicht
- 申请人地址: DE Berlin
- 专利权人: Schering AG
- 当前专利权人: Schering AG
- 当前专利权人地址: DE Berlin
- 代理机构: Millen, White, Zelano, Branigan, P.C.
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/08 ; A61K9/10 ; A61K9/70 ; A61K31/56
摘要:
A formulation for male contraception comprising a progestin possessing both estrogenic and androgenic properties is remarkably effective for spermatogenesis suppression in males. The progestin Norethisterone (NET), particularly its derivatives Norethisterone acetate and Norethisterone enanthate in sufficient doses induce oligozoospermia or azoospermia in males. Formulations further comprising an androgen, such as a testosterone derivative such as a testosterone ester, particularly testosterone undecanoate, are especially effective male contraceptive formulations.
公开/授权文献
- US20020103176A1 Male contraceptive formulation comprising norethisterone 公开/授权日:2002-08-01
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