发明授权
- 专利标题： Retinol derivatives, the method of preparations and the uses thereof
- 专利标题（中）： 视黄醇衍生物，制剂方法及其应用
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申请号： US10221428申请日： 2002-01-10
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公开(公告)号： US07030265B2公开(公告)日： 2006-04-18
- 发明人: Hong-Sig Sin , Si-Ho Park , Young-Soy Rho , Soo-Jong Um , Youn-Ja Kwon , Myoung-Soon Park , Hye-Sook Han , Min-Sook Jung , So-Mi Kim-Cho , Dong-Myong Kim , Deok-kun Oh , Jong-Sup Park
- 申请人： Hong-Sig Sin , Si-Ho Park , Young-Soy Rho , Soo-Jong Um , Youn-Ja Kwon , Myoung-Soon Park , Hye-Sook Han , Min-Sook Jung , So-Mi Kim-Cho , Dong-Myong Kim , Deok-kun Oh , Jong-Sup Park
- 申请人地址： KR Seoul
- 专利权人： Chebigen, Inc.
- 当前专利权人： Chebigen, Inc.
- 当前专利权人地址： KR Seoul
- 代理机构： Jones Day
- 优先权： KR2001/1667 20010111; KR2002/1178 20020109
- 国际申请： PCT/KR02/00041 WO 20020110
- 国际公布： WO02/055540 WO 20020718
- 主分类号： C07C69/07
- IPC分类号： C07C69/07 ; C07C69/52 ; C07C69/527 ; C07C69/587
摘要：
The present invention relates to novel retinol derivatives, the methods of preparation and the uses thereof. According to the present invention, retinol derivatives comprise carboester linkage between di-, tri-, polypeptide having functional group of COOH and retinol. Retinol derivatives in the present invention comprise carboester linkage between amino acid having functional group of di-COOH and retinol. Retinol derivatives comprise carboester linkage between retinol and the compounds having the function group of COOH and multiple double bonds on carbon chain. Retinol derivatives in the present invention comprise carboester linkage between retinol and the compounds having the functional group of di-COOH and one double bond. Retinol derivatives in the present invention comprise ether linkage between the compounds with OH functional group and retinol.