发明授权
- 专利标题： Di-substituted pyrrolotriazine compounds
- 专利标题（中）： 二取代吡咯并三嗪化合物
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申请号： US11019899申请日： 2004-12-22
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公开(公告)号： US07064203B2公开(公告)日： 2006-06-20
- 发明人: Ashvinikumar V. Gavai , Wen-Ching Han , Ping Chen , Edward H. Ruediger , Harold Mastalerz , Brian E. Fink , Derek J. Norris
- 申请人： Ashvinikumar V. Gavai , Wen-Ching Han , Ping Chen , Edward H. Ruediger , Harold Mastalerz , Brian E. Fink , Derek J. Norris
- 申请人地址： US NJ Princeton
- 专利权人： Bristol Myers Squibb Company
- 当前专利权人： Bristol Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Elliott Korsen
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/53 ; A61P19/02
摘要：
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The compounds of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
公开/授权文献
- US20050197339A1 Di-substituted pyrrolotrizine compounds 公开/授权日：2005-09-08
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