Invention Grant
US07067283B2 Producing telomerase activators and inhibitors by screening with purified telomerase
失效
通过用纯化的端粒酶筛选生产端粒酶激活剂和抑制剂
- Patent Title: Producing telomerase activators and inhibitors by screening with purified telomerase
- Patent Title (中): 通过用纯化的端粒酶筛选生产端粒酶激活剂和抑制剂
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Application No.: US10811033Application Date: 2004-03-26
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Publication No.: US07067283B2Publication Date: 2006-06-27
- Inventor: Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
- Applicant: Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
- Applicant Address: US CA Menlo Park
- Assignee: Geron Corporation
- Current Assignee: Geron Corporation
- Current Assignee Address: US CA Menlo Park
- Agent J. Michael Schiff; David J. Earp
- Main IPC: C12Q1/42
- IPC: C12Q1/42 ; C12Q1/68
Abstract:
This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
Public/Granted literature
- US20050089883A1 Producing telomerase activators and inhibitors by screening with purified telomerase Public/Granted day:2005-04-28
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