-
1.发明授权公开(公告)号：US06787133B2
公开(公告)日：2004-09-07
申请号：US10330872
申请日：2002-12-24
Applicant: Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
Inventor： Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
IPC: A61K3851
CPC classification number: C12N9/1241 , A61K39/00 , C12Y207/07049 , Y10S435/935
Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
Abstract translation: 本发明提供了纯化的端粒酶及其纯化方法。 该方法包括使用几个连续的步骤，包括使用结合带负电荷的分子的基质，结合带正电荷的分子的基质，中间选择性基质，基于其大小，形状或浮力密度分离分子的方法， 并通过亲和纯化。
-
公开(公告)号：US06777203B1
公开(公告)日：2004-08-17
申请号：US09244438
申请日：1999-02-04
Applicant: Gregg B. Morin , Serge P. Lichtsteiner , Alain P. Vasserot , Robert R. Adams , William H. Andrews
Inventor： Gregg B. Morin , Serge P. Lichtsteiner , Alain P. Vasserot , Robert R. Adams , William H. Andrews
IPC: C12P2106
CPC classification number: C12N9/1276 , A01K67/0271 , A01K2217/05 , A01K2217/30 , A01K2227/105 , A01K2267/0331 , A01K2267/0393 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N7/00 , C12N9/1241 , C12N15/1137 , C12N15/8509 , C12N2310/15 , C12N2310/315 , C12N2795/10343 , C12Y207/07049
Abstract: The present invention is related to novel nucleic acids comprising telomerase reverse transcriptase (TERT) cis-acting transcriptional control sequences, including TERT human and mouse promoter sequences. The present invention is further directed to methods of using these cis-acting transcriptional control sequences, for example, to drive heterologous gene sequences; to modulate the level of transcription of TERT or to isolate novel trans-acting regulatory factors which bind to and modulate the activity of a TERT promoter.
Abstract translation: 本发明涉及包含端粒酶逆转录酶（TERT）顺式作用转录控制序列的新型核酸，包括TERT人和小鼠启动子序列。 本发明还涉及使用这些顺式作用转录控制序列的方法，例如驱动异源基因序列; 以调节TERT的转录水平或分离结合并调节TERT启动子的活性的新的反式作用调节因子。
-
Patent Agency Ranking
公开(公告)号：US06261556B1
公开(公告)日：2001-07-17
申请号：US09420056
申请日：1999-10-18
Applicant: Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan , James T. Kealey
Inventor： Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan , James T. Kealey
IPC: A61K3851
CPC classification number: C12N9/1241 , A61K39/00 , C12Y207/07049
Abstract: This invention provides purified human telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of a first matrix that binds molecules bearing negative charges, a matrix that binds molecules bearing positive charges, a second matrix that binds molecules bearing negative charges, an affinity purification step and a matrix that separates molecules according to their size.
Abstract translation: 本发明提供纯化的人端粒酶及其纯化方法。 该方法包括使用几个连续的步骤，包括使用结合带有负电荷的分子的第一基质，结合带正电荷的分子的基质，结合带负电荷的分子的第二基质，亲和纯化步骤和基质 根据其大小分离分子。
-
4.发明授权Producing telomerase activators and inhibitors by screening with purified telomerase 失效通过用纯化的端粒酶筛选生产端粒酶激活剂和抑制剂公开(公告)号：US07067283B2
公开(公告)日：2006-06-27
申请号：US10811033
申请日：2004-03-26
Applicant: Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
Inventor： Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
CPC classification number: C12N9/1241 , A61K39/00 , C12Y207/07049 , Y10S435/935
Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
Abstract translation: 本发明提供了纯化的端粒酶及其纯化方法。 该方法包括使用几个连续的步骤，包括使用结合带负电荷的分子的基质，结合带正电荷的分子的基质，中间选择性基质，基于其大小，形状或浮力密度分离分子的方法， 并通过亲和纯化。
-
公开(公告)号：US06517834B1
公开(公告)日：2003-02-11
申请号：US09717828
申请日：2000-11-20
Applicant: Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
Inventor： Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
IPC: A61K3851
CPC classification number: C12N9/1241 , A61K39/00 , C12Y207/07049 , Y10S435/935
Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
Abstract translation: 本发明提供了纯化的端粒酶及其纯化方法。 该方法包括使用几个连续的步骤，包括使用结合带负电荷的分子的基质，结合带正电荷的分子的基质，中间选择性基质，基于其大小，形状或浮力密度分离分子的方法， 并通过亲和纯化。
-
公开(公告)号：US06545133B1
公开(公告)日：2003-04-08
申请号：US09717829
申请日：2000-11-20
Applicant: Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
Inventor： Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan
IPC: A23J100
CPC classification number: C12Y207/07049 , A61K39/00 , C12N9/1241
Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
Abstract translation: 本发明提供了纯化的端粒酶及其纯化方法。 该方法包括使用几个连续的步骤，包括使用结合带负电荷的分子的基质，结合带正电荷的分子的基质，中间选择性基质，基于其大小，形状或浮力密度分离分子的方法， 并通过亲和纯化。
-
公开(公告)号：US5968506A
公开(公告)日：1999-10-19
申请号：US833377
申请日：1997-04-04
Applicant: Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan , James T. Kealey
Inventor： Scott L. Weinrich , Edward M. Atkinson, III , Serge P. Lichtsteiner , Alain P. Vasserot , Ronald A. Pruzan , James T. Kealey
CPC classification number: C12N9/1241 , C12Y207/07049 , A61K39/00
Abstract: This invention provides purified human telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of a first matrix that binds molecules bearing negative charges, a matrix that binds molecules bearing positive charges, a second matrix that binds molecules bearing negative charges, an affinity purification step and a matrix that separates molecules according to their size.
Abstract translation: 本发明提供纯化的人端粒酶及其纯化方法。 该方法包括使用几个连续的步骤，包括使用结合带有负电荷的分子的第一基质，结合带正电荷的分子的基质，结合带负电荷的分子的第二基质，亲和纯化步骤和基质 根据其大小分离分子。
-
-
-
-
-
-
Search Results
7
records
(took 0.015 seconds)
