Provided are compositions suitable for use in forming a flexible optical waveguide. The compositions include a polymer that has units of the formula (R1SiO1.5) and (R22SiO), wherein R1 and R2 are the same or different, and are substituted and/or unsubstituted organic groups, and wherein the (R22SiO) units are present in an amount of 14 wt % or more based on the polymer; and a plurality of functional end and/or internal groups. Also included is a component for altering the solubility of the composition upon activation. The solubility of the composition in a dried state is alterable upon activation of the component such that the composition is developable in an aqueous developer solution. Also provided are flexible optical waveguides, methods of forming flexible optical waveguides and electronic devices that include a flexible optical waveguide.