发明授权
- 专利标题： α-1,3-fucosyltransferase
- 专利标题（中）： α-1,3-岩藻糖基转移酶
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申请号： US08361306申请日： 1994-11-29
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公开(公告)号： US07094530B1公开(公告)日： 2006-08-22
- 发明人: Katsutoshi Sasaki , Kazumi Miura , Nobuo Hanai , Tatsunari Nishi
- 申请人： Katsutoshi Sasaki , Kazumi Miura , Nobuo Hanai , Tatsunari Nishi
- 申请人地址： JP Tokyo
- 专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Nixon & Vanderhye P.C.
- 优先权： JP5-069016 19930329
- 主分类号： C12N15/54
- IPC分类号： C12N15/54 ; C12N9/10 ; C12P19/18 ; C12Q1/68
摘要：
The invention provides a novel species of α-1,3-fucosyltransferase expressed by a gene cloned from animal cells, a cDNA coding for the α-1,3-fucosyltransferase, a method of detecting, or inhibiting the production of, the α-1,3-fucosyltransferase which involves the use of the cDNA, a recombinant vector containing the DNA as an insert, a cell harboring the recombinant vector, and a method of producing same. The α-1,3-fucosyltransferase of the invention is useful in the production of carbohydrate chains having useful physiological activity, for example sialyl Lewis x, and modifications thereof.
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