Invention Grant
US07098018B2 Aminopeptidase derived from bacillus licheniformis, gene encoding the aminopeptidase, expression vector containing the gene, transformant and method for preparation thereof
有权
源自地衣芽孢杆菌的氨基肽酶,编码氨基肽酶的基因,含有该基因的表达载体,转化体及其制备方法
- Patent Title: Aminopeptidase derived from bacillus licheniformis, gene encoding the aminopeptidase, expression vector containing the gene, transformant and method for preparation thereof
- Patent Title (中): 源自地衣芽孢杆菌的氨基肽酶,编码氨基肽酶的基因,含有该基因的表达载体,转化体及其制备方法
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Application No.: US10481531Application Date: 2002-07-06
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Publication No.: US07098018B2Publication Date: 2006-08-29
- Inventor: Young-Phil Lee , Seung-won Lee , Chul-ho Jung , Hyung-Cheol Kim , Soon-Yong Choi , Jin-suk Kim , Hyun-Sik Kim , Jung-Woo Seo
- Applicant: Young-Phil Lee , Seung-won Lee , Chul-ho Jung , Hyung-Cheol Kim , Soon-Yong Choi , Jin-suk Kim , Hyun-Sik Kim , Jung-Woo Seo
- Applicant Address: KR Seoul
- Assignee: LG Life Sciences Ltd.
- Current Assignee: LG Life Sciences Ltd.
- Current Assignee Address: KR Seoul
- Agency: Swanson & Bratschun, L.L.C.
- Priority: KR2001-40268 20010706; KR2002-30798 20020531
- International Application: PCT/KR02/01280 WO 20020706
- International Announcement: WO03/004635 WO 20030116
- Main IPC: C12N9/56
- IPC: C12N9/56 ; C12N15/57 ; C12N15/74 ; C12P21/06

Abstract:
The present invention relates to novel aminopeptidase derived from Bacillus licheniformis, a gene encoding the aminopeptidase, an expression vector containing the gene, a cell transformant transfected with the expression vector and a process for preparing a natural type protein using thereof. More particularly, the present invention relates to a gene encoding aminopeptidase which is cloned and manufactured using the recombinant DNA technique, an expression vector containing the gene, a cell transformant transfected with the expression vector and a recombinant aminopeptidase which is necessary to produce recombinant human growth hormone in a natural type protein and can be expressed in a high yield more stably and advantageously, compared with conventional methods for the purification.
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