发明授权
US07108998B2 Nucleic acid fragment encoding an NRPS for the biosynthesis of anthramycin
失效
核苷酸片段编码NRPS用于生物合成奥匹他霉素
- 专利标题： Nucleic acid fragment encoding an NRPS for the biosynthesis of anthramycin
- 专利标题（中）： 核苷酸片段编码NRPS用于生物合成奥匹他霉素
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申请号： US10166087申请日： 2002-06-11
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公开(公告)号： US07108998B2公开(公告)日： 2006-09-19
- 发明人: Chirs M. Farnet , Alfredo Staffa
- 申请人： Chirs M. Farnet , Alfredo Staffa
- 申请人地址： CA Saint-Laurent
- 专利权人： Ecopia Biosciences inc.
- 当前专利权人： Ecopia Biosciences inc.
- 当前专利权人地址： CA Saint-Laurent
- 代理商 Ywe J. Looper
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12P1/00 ; C12N1/20
摘要：
Genes and proteins involved in the biosynthesis of benzodiazepines by microorganisms, including the genes and proteins forming the biosynthetic loci for the benzodiazepine anthramycin from Streptomyces refuineus subsp. thermotolerans including non-ribosomal peptide synthetases (NRPS). The genes and proteins allow direct manipulation of benzodiazepines and related chemical structures via chemical engineering of the enzymes involved in the biosynthesis of anthramycin.
公开/授权文献
- US20030077767A1 Genes and proteins for the biosynthesis of anthramycin 公开/授权日：2003-04-24
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