- 专利标题： Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
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申请号： US11093991申请日： 2005-03-30
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公开(公告)号： US07109347B2公开(公告)日： 2006-09-19
- 发明人: Stephan von Hoersten , Hans-Ulrich Demuth , Torsten Hoffmann
- 申请人： Stephan von Hoersten , Hans-Ulrich Demuth , Torsten Hoffmann
- 申请人地址： DE Halle (Saale)
- 专利权人： Probiodrug AG
- 当前专利权人： Probiodrug AG
- 当前专利权人地址： DE Halle (Saale)
- 代理机构： Sonnenschein Nath & Rosenthal LLP
- 优先权： EP01114796 20010627; DE10150203 20011012; DE10154689 20011109
- 主分类号： C07D277/04
- IPC分类号： C07D277/04 ; C07D277/16 ; C07D277/18 ; C07D207/00 ; C07D295/00 ; C07D291/00 ; C07D291/02 ; C07D291/04
摘要：
The present invention provides new uses of DPIV-inhibitors of the present invention, and their corresponding pharmaceutically acceptable acid addition salt forms, for treating conditions mediated by DPIV or DPIV-like enzymes, such as cancer and tumors. In a more preferred embodiment, the compounds of the present invention are useful for the treatment of metastasis and tumor colonization.
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