发明授权
- 专利标题： Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
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申请号： US10699563申请日： 2003-11-03
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公开(公告)号： US07112595B2公开(公告)日： 2006-09-26
- 发明人: Bradford Van Wagenen , Thomas M. Stormann , Scott T Moe , Susan M Sheehan , Donald McLeod , Daryl L Smith , Methvin Isaac , Abdelmalik Slassi , Ian Egle , Louise Edwards , Tomislav Stefanac , Tao Xin , Jalaj Arora , William Michne
- 申请人： Bradford Van Wagenen , Thomas M. Stormann , Scott T Moe , Susan M Sheehan , Donald McLeod , Daryl L Smith , Methvin Isaac , Abdelmalik Slassi , Ian Egle , Louise Edwards , Tomislav Stefanac , Tao Xin , Jalaj Arora , William Michne
- 申请人地址： US UT Salt Lake City SE Sodertalje
- 专利权人： NPS Pharmaceuticals, Inc.,Astrazeneca AB
- 当前专利权人： NPS Pharmaceuticals, Inc.,Astrazeneca AB
- 当前专利权人地址： US UT Salt Lake City SE Sodertalje
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D401/02
摘要：
The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
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