Invention Grant
- Patent Title: Arrays of nucleic acid probes on biological chips
- Patent Title (中): 生物芯片上的核酸探针阵列
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Application No.: US08510521Application Date: 1995-08-02
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Publication No.: US07115364B1Publication Date: 2006-10-03
- Inventor: Mark Chee , Maureen T. Cronin , Stephen P. A. Fodor , Thomas R. Gingeras , Xiaohua C. Huang , Earl A. Hubbell , Robert J. Lipshutz , Peter E. Lobban , Charles Garrett Miyada , Macdonald S. Morris , Nila Shah , Edward L. Sheldon
- Applicant: Mark Chee , Maureen T. Cronin , Stephen P. A. Fodor , Thomas R. Gingeras , Xiaohua C. Huang , Earl A. Hubbell , Robert J. Lipshutz , Peter E. Lobban , Charles Garrett Miyada , Macdonald S. Morris , Nila Shah , Edward L. Sheldon
- Applicant Address: US CA Santa Clara
- Assignee: Affymetrix, Inc.
- Current Assignee: Affymetrix, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/50 ; G01N33/53 ; C07H21/04
Abstract:
The invention provides chips of immobilized probes, and methods employing the chips, for comparing a reference polynucleotide sequence of known sequence with a target sequence showing substantial similarity with the reference sequence, but differing in the presence of e.g., mutations.
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