发明授权
- 专利标题： PAK2: modulators of lymphocyte activation
- 专利标题（中）： PAK2：淋巴细胞活化调节剂
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申请号： US09967624申请日： 2001-09-28
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公开(公告)号： US07118854B2公开(公告)日： 2006-10-10
- 发明人: X. Charlene Liao , Peter Chu , Jorge Pardo , Congfen Li , Haoran Zhao , Jun Wu
- 申请人： X. Charlene Liao , Peter Chu , Jorge Pardo , Congfen Li , Haoran Zhao , Jun Wu
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： C12Q1/70
- IPC分类号： C12Q1/70 ; C12Q1/68 ; C07H21/04
摘要：
The present invention relates to regulation of lymphocyte activation. More particularly, the present invention is directed to nucleic acids encoding PAK2, which is involved in modulation of lymphocyte activation. The invention further relates to methods for identifying and using agents, including small organic molecules, peptides, circular peptides, antibodies, lipids, antisense nucleic acids, and ribozymes, that modulate lymphocyte activation via modulation of PAK2; as well as to the use of expression profiles and compositions in diagnosis and therapy related to lymphocyte activation and suppression.
公开/授权文献
- US20020142325A1 PAK 2: modulators of lymphocyte activation 公开/授权日：2002-10-03
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