Invention Grant
- Patent Title: SYK-UBP polypeptides and methods of making and isolating same
- Patent Title (中): SYK-UBP多肽及其制备和分离方法
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Application No.: US10088960Application Date: 2000-09-25
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Publication No.: US07122630B1Publication Date: 2006-10-17
- Inventor: Ying Luo , Helena Mancebo
- Applicant: Ying Luo , Helena Mancebo
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Townsend and Townsend and Crew LLP
- Agent Annette S. Parent
- International Application: PCT/US00/26338 WO 20000925
- International Announcement: WO01/21654 WO 20010329
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C12N15/00 ; C12N15/12 ; C12N15/63 ; C07H21/04
Abstract:
The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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