- 专利标题： Pyrrole substituted 2-indolinone protein kinase inhibitors
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申请号： US11028477申请日： 2005-01-04
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公开(公告)号： US07125905B2公开(公告)日： 2006-10-24
- 发明人: Peng Cho Tang , Todd A. Miller , Xiaoyuan Li , Li Sun , Chung Chen Wei , Shahrzad Shirazian , Congxin Liang , Tomas Vojkovsky , Asaad S. Nematalla , Michael Hawley
- 申请人： Peng Cho Tang , Todd A. Miller , Xiaoyuan Li , Li Sun , Chung Chen Wei , Shahrzad Shirazian , Congxin Liang , Tomas Vojkovsky , Asaad S. Nematalla , Michael Hawley
- 申请人地址： US CA San Diego
- 专利权人： Agouron Pharmaceuticals, Inc.
- 当前专利权人： Agouron Pharmaceuticals, Inc.
- 当前专利权人地址： US CA San Diego
- 代理商 Stephen D. Prodnuk; Bryan C. Zielinski
- 主分类号： A61K31/404
- IPC分类号： A61K31/404 ; C07D403/06
摘要：
The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.