- 专利标题： Glucocorticoid receptor ligands for the treatment of metabolic disorders
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申请号： US10460491申请日： 2003-06-12
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公开(公告)号： US07141559B2公开(公告)日： 2006-11-28
- 发明人: Richard D. Bishop , Russell Drew Cink , Bradley D. Gates , Lars T. Hagberg , Peer B. Jacobsen , Philip R. Kym , Chunqiu Lai , Marvin Robert Leanna , James T. Link , Steven J. Richards , Noah Tu , Tom W. von Geldern
- 申请人： Richard D. Bishop , Russell Drew Cink , Bradley D. Gates , Lars T. Hagberg , Peer B. Jacobsen , Philip R. Kym , Chunqiu Lai , Marvin Robert Leanna , James T. Link , Steven J. Richards , Noah Tu , Tom W. von Geldern
- 申请人地址： SE
- 专利权人： Karo Bio AB
- 当前专利权人： Karo Bio AB
- 当前专利权人地址： SE
- 代理机构： Wiggin and Dana LLP
- 代理商 Todd E. Garabedian; Elizabeth A. Galletta
- 主分类号： A61K31/575
- IPC分类号： A61K31/575 ; C07J9/00
摘要：
This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.
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