发明授权
- 专利标题: Cap-binding protein
- 专利标题(中): Cap结合蛋白
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申请号: US10530886申请日: 2003-10-09
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公开(公告)号: US07141650B2公开(公告)日: 2006-11-28
- 发明人: Tamaki Oda , Hideki Endoh , Yoshitaka Ueda , Kazunori Inabe
- 申请人: Tamaki Oda , Hideki Endoh , Yoshitaka Ueda , Kazunori Inabe
- 申请人地址: JP Tokyo
- 专利权人: Astellas Pharma, Inc.
- 当前专利权人: Astellas Pharma, Inc.
- 当前专利权人地址: JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2002-298549 20021011
- 国际申请: PCT/JP03/12968 WO 20031009
- 国际公布: WO2004/033688 WO 20040422
- 主分类号: A61K14/00
- IPC分类号: A61K14/00
摘要:
A novel polypeptide which is useful in screening of an agent for improving insulin resistance and an agent for improving glucose metabolism, a polynucleotide encoding the polypeptide, an expression vector comprising the polynucleotide, and a cell transformed with the expression vector are disclosed. The polypeptide is a protein expressed in skeletal muscle. When the protein is overexpressed, incorporation of sugar into a cell is inhibited.A method for screening of an agent for improving insulin resistance and/or an agent for improving glucose metabolism in which the polypeptide is used, and a method for producing a pharmaceutical composition for insulin resistance and/or glucose metabolism improvement comprising a substance obtained according to the method for screening as an active ingredient are also disclosed.
公开/授权文献
- US20060008857A1 Cap-binding protein 公开/授权日:2006-01-12