Invention Grant
US07148054B2 Evolution of whole cells and organisms by recursive sequence recombination
有权
通过递归序列重组进行全细胞和生物体的进化
- Patent Title: Evolution of whole cells and organisms by recursive sequence recombination
- Patent Title (中): 通过递归序列重组进行全细胞和生物体的进化
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Application No.: US10194686Application Date: 2002-07-11
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Publication No.: US07148054B2Publication Date: 2006-12-12
- Inventor: Stephen delCardayre , Matthew Tobin , Willem P. C. Stemmer , Jon E. Ness , Jeremy Minshull , Phillip Patten , Venkiteswatan Subramanian , Linda A. Castle , Claus M. Krebber , Steve Bass , Ying-Xin Zhang , Tony Cox , Gjalt Huisman , Ling Yuan , Joseph A. Affholter
- Applicant: Stephen delCardayre , Matthew Tobin , Willem P. C. Stemmer , Jon E. Ness , Jeremy Minshull , Phillip Patten , Venkiteswatan Subramanian , Linda A. Castle , Claus M. Krebber , Steve Bass , Ying-Xin Zhang , Tony Cox , Gjalt Huisman , Ling Yuan , Joseph A. Affholter
- Applicant Address: US CA Redwood City
- Assignee: Maxygen, Inc.
- Current Assignee: Maxygen, Inc.
- Current Assignee Address: US CA Redwood City
- Agent Norman J. Kruse; Joanne R. Petithory
- Main IPC: C12N1/16
- IPC: C12N1/16 ; C12N1/18
Abstract:
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
Public/Granted literature
- US20030148309A1 Evolution of whole cells and organisms by recursive sequence recombination Public/Granted day:2003-08-07
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