发明授权
- 专利标题: Distributed multi-segmented reconfigurable traveling wave grids for separation of proteins in gel electrophoresis
- 专利标题(中): 分布式多分段可重构行波网格,用于在凝胶电泳中分离蛋白质
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申请号: US10459799申请日: 2003-06-12
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公开(公告)号: US07156970B2公开(公告)日: 2007-01-02
- 发明人: Meng H. Lean , Huangpin Ben Hsieh , John S. Fitch , Armin R. Völkel , Bryan Preas , Scott Elrod , Richard H. Bruce , Eric Peeters , Frank Torres , Michael Chabinyc
- 申请人: Meng H. Lean , Huangpin Ben Hsieh , John S. Fitch , Armin R. Völkel , Bryan Preas , Scott Elrod , Richard H. Bruce , Eric Peeters , Frank Torres , Michael Chabinyc
- 申请人地址: US CA Palo Alto
- 专利权人: Palo Alto Research Center Incorporated
- 当前专利权人: Palo Alto Research Center Incorporated
- 当前专利权人地址: US CA Palo Alto
- 代理机构: Fay, Sharpe, Fagan, Minnich & McKee, LLP
- 主分类号: G01N27/447
- IPC分类号: G01N27/447 ; G01N27/453
摘要:
Various traveling wave grids and electrophoretic systems, and electrode assemblies using such grids, are disclosed. A configuration in which a voltage potential is used to load a biomolecule sample against a grid is disclosed. A unique strategy of using multiple, reconfigurable grids in such systems is also described. The strategy involves initially conducting a broad protein separation and then selectively tailoring one or more grids, and conducting one or more secondary processing operations. Related strategies and specific methods are additionally disclosed for separating samples of biomolecules and components thereof using the noted systems, assemblies, and grids.