发明授权
- 专利标题： Staphylococcus aureus exopolysaccharide and process
- 专利标题（中）： 金黄色葡萄球菌外多糖和过程
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申请号： US10498070申请日： 2002-12-06
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公开(公告)号： US07157443B2公开(公告)日： 2007-01-02
- 发明人: Joseph G. Joyce , James C. Cook, III , Chitrananda Abeygunawardana , Karen M. Grimm , Craig T. Przysiecki , Robert W. Hepler , Charlotte C. Ip , Keith Roper , Qiuwei Xu , Kathrin U. Jansen , Paul M. Keller , Leslie D. Cope
- 申请人： Joseph G. Joyce , James C. Cook, III , Chitrananda Abeygunawardana , Karen M. Grimm , Craig T. Przysiecki , Robert W. Hepler , Charlotte C. Ip , Keith Roper , Qiuwei Xu , Kathrin U. Jansen , Paul M. Keller , Leslie D. Cope
- 申请人地址： US NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： US NJ Rahway
- 代理商 Joan E. Switzer; Joanne M. Giesser
- 国际申请： PCT/US02/39079 WO 20021206
- 国际公布： WO03/053462 WO 20030703
- 主分类号： A61K31/715
- IPC分类号： A61K31/715 ; A61K39/02 ; C07H1/00
摘要：
A high molecular weight polysaccharide intracellular adhesin (SAE) antigen having the general structure of poly-1,6,β-2-amidoglucopyranoside, which is variable substituted with N-acetyl and O-succinyl substituents is described. Also, a method is given for isolating this antigen from Staphylococcus aureus. The SAE can be used in a vaccine, either alone, conjugated to an immunogenic protein, and/or with an immunogenic adjuvant.
公开/授权文献
- US20040259838A1 Staphylococcus aureus exopolysaccharide and process 公开/授权日：2004-12-23
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